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Closing perspectives: Balancing antioxidant activities and redox signaling We now know that in hepatocytes and perhaps in many metazoan cell types, cytosolic disulfide reducing power can come from NADPH via TrxR1, from NADPH via Gsr, or from Met catabolism [107]

45% of this volume is cellular part and 55% noncellular part, of which 90% of the noncellular part is plasma, and so the volume of plasma in the central compartment is approximately greater than 3 L

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