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Altered brain-gut axis in autism: comorbidity or causative mechanisms

The central hypothesis is that diabetic hyperglycemia causes a pseudohypoxic increase in the NADH/NAD + ratio and reductive stress (57, 103)

The naturally occurring endocannabinoid anandamide also caused similar 24 h loss of cell viability in developing mouse cortical neurons at concentrations ranging from 1 to 100 mcg/mL, indicating the mechanism of cell death could be mediated through the cannabinoid receptors

It attaches to the uterine wall and the umbilical cord which connects between the mother and the fetus, thus supporting the growth and development of the fetus [1]