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If fatty acid oxidation is defective, fat cannot be utilized, glucose is consumed without regeneration via gluconeogenesis (due to inhibition of pyruvate carboxylase), ketones cannot be produced and there is a drop in glucose levels (hypoglycemia)
As the baseline renal clearance of acetyl-l-carnitine (and l-carnitine) is substantially lower than the glomerular filtration rate, extensive (9899%) tubular reabsorption occurs
Acne predominantly appears during adolescence, but is also increasingly common in adulthood (173)
