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Engages brainstem and hypothalamic circuits (notably in the area postrema and related nuclei) to decrease food intake, increase satiety, slow gastric emptying, and ultimately lower body weight in animal and human studies

Fraga-Corral M, Otero P, Cassani L, Echave J, Garcia-Oliveira P, Carpena M, Chamorro F, Lourenco-Lopes C, Prieto MA, Simal-Gandara J (2021) Traditional applications of tannin rich extracts supported by scientific data: chemical composition, bioavailability and bioaccessibility

doi: 10.1111/ejn.12877 98 LimCSKimHYuNKKangSJKimTKoHGet al

A scalp serum may help some patients, but it should not delay a proper workup if hair loss is sudden, patchy, severe, or getting worse