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Other potential mechanisms underlying the action of NAC on neuropathic pain include the activation of type-9 matrix metalloprotease and the decreased phosphorylation of p38 MAP kinase in the spinal cord [167, 168]
Therefore, the secretion factor of MSC-CM exerts a neuroprotective effect

Nelson K,Jackson A,Gingerich T,Fahlman A,Lessenich C,Fennell F,Ventura D,Roy P,Keith D,Sheppard B,Brody JR,Mills GB,Ronai ZA,Sears RC
Molecular pathways: metabolic control of histone methylation and gene expression in cancer
