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The accumulation of ROS induced by ES exceeds the antioxidant defense capabilities of cancer cells (such as the glutathione system), triggering the collapse of mitochondrial membrane potential and ultimately leading to apoptosis (Wen et al., 2023

10.1016/j.cellimm.2016.07.007 65 LeeS

The unique microenvironmental and intrinsic cell properties of brain tumors have made them practically resistant to majority of conventional and cutting-edged therapies [3]

J., Haider, M
