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These included the orbitofrontal cortex and medial prefrontal cortex (PFC), subgenual cingulate cortex (SGCC), inferior and superior temporal gyri, primary motor cortex, and supramarginal gyrus

The medicine is virtually non-toxic and has very few drug interactions

If oral B12 replacement has been trialled in a person with metformin-associated B12 deficiency, I would suggest that a repeat measurement of B12 levels after 812 weeks is a good time to reassess whether absorption is adequate or whether a switch to intramuscular replacement is required

One is cyanocobalamin and second is methyl cobalamin
