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Description
Several biophysical studies reported that lipid-free ApoE4 is more aggregation-prone than lipid-free ApoE3, suggesting that aggregation may play an essential role in driving the pathological effects of ApoE4 [33, 34]

Keating, C

Another study found that paclitaxel induced significant upregulation in IL-1, IL-1, IL-6, TNF-, INF- and MCP-1, which was attenuated by a TNF-alpha monoclonal antibody (etanercept) [1] In a vincristine CIPN model, the anti-inflammatory cytokine, IL-4, and associated STAT signalling was reduced, with an increase in pro-inflammatory cytokines such as IL-1-beta and TNF-alpha[92]

Hepatology 47 , 596604 (2008)
