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THE HUMAN NQO1 GENE EXPRESSION NAD(P)H:quinone oxidoreductase 1 (NQO1) (originally known as DT-diaphorase,) is a flavoenzyme that plays a crucial role in protecting cells from a broad range of substrates by catalyzing two- and four-electron reductions of endogenous and exogenous quinones to their hydroquinone forms [ 9 ]

A total of 50 g of soluble protein was loaded onto the column by manually adjusting the injection volume for each sample

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The brain concentrations and B/P ratios of risperidone (13.1-fold and 12-fold) and 9-hydroxyrisperidone (29.4-fold and 29-fold) were significantly higher in the ABCB1 knockout mice than wild-type mice