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Relationship between serum B 12 concentrations and mortality: experience in NHANES.BMC Med2020;18:307

Additionally, 1,8-diMQ and 5-amino-1MQ showed little inhibition of COMT at maximal tested concentrations of 200 M (20% inhibition) and 600 M (10% inhibition), respectively, although no clear trend of concentration-dependent inhibition was observed

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This treatment should be continued for at least three months before any improvement in spermatogenesis can be expected
