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Compound I features a configuration with an iron-oxo species (Fe=O) and a porphyrin radical cation, preparing it for further reaction [46]
Because the genetic loss is too small to be detected by standard karyotyping, definitive diagnosis requires fluorescence in situ hybridization or chromosomal microarray testing
Interestingly, ASCL1 is broadly distributed and has a distinct preference for oleate and linoleate, 390 suggesting that it may be a candidate to regulate the intercellular phospholipid distribution of some octadecanoids
10.1016/j.ijpharm.2022.122570 63 Le NedelecM.GlueP.WinterH.GoultonC.MedlicottN
