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223 , 101 (2016) L

Multivalent binding of ZSWIM8 and AGO2 Following the ZSWIM8 dimeric E3 superdomain is a helix- and loop-rich region (residues 290915) we term the TDMD sensor because it detects most features imparted by the trigger RNA to the AGO2miR-7 complex

In fact, its ability to mediate inflammatory signaling pathways and inhibit the activation of NF-B provides a basis for its potent anti-inflammatory effects

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