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This flexibility allows researchers to produce a final protein product that is free of the affinity tag, which may be necessary for certain functional assays or structural studies
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it was a targeted, functional response
In addition, elevated methylation of histone H3 lysine 27 (H3K27me3) by EZH2 further stabilizes this reversible quiescent state by repressing lineage-specific gene expression programs (Marso et al., 2022)
