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The field is moving fast and formal veterinary education hasnt caught up
The binding of GH to GH-R in the liver promotes the synthesis of IGF-1, ALS, and IGFB3 a complex that determines the circulating half-life and, thus, peripheral effects of IGF-1
Higher doses can stall the same process or even tip into toxicity over longer exposures, where free copper drifting loose from the complex starts driving oxidative damage
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