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True acne fulminans is a very rare complication requiring aggressive management

These systems include a) enzymatic defences such as catalase, superoxide dismutase and glutathione that inhibit the formation of toxic OH - by metabolizing superoxide, H 2 O 2 and lipid peroxides, and b) entrapping free radical defences such as histidine-peptides, the iron-binding proteins transferring and ferritin, dihydrolipoic acid, reduced CoQ 10 , melatonin, urate and plasma protein thiols [24, 191-193]

[DOI] [PMC free article] [PubMed] [Google Scholar] Moreno EMoreno-Delgado DNavarro GHoffmann HMFuentes SRosell-Vilar SGasperini PRodrguez-Ruiz MMedrano MMallol J, et al

[Google Scholar] 4.Pauling L