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In ME/CFS, this protective mechanism is severely compromised

What is the best human evidence at that dose

J.RooneyB.et al

A peer-reviewed study in the Journal of Clinical Endocrinology and Metabolism by Prinz and colleagues demonstrating that acute alcohol intake produces a significant suppression of nocturnal growth hormone secretion alongside reduced slow-wave sleep has been the foundational reference for this effect for decades, and the relationship has been replicated in newer literature on adult sleep architecture
