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Keywords: Brain fog, Neuroinflammation, Gut-brain axis, Gastrointestinal health, Sleep, Diet Introductin The term brain fog is increasingly used informally to describe difficulties in cognitive function

53 Our results suggest the critical role of Nrf2/Keap1 pathway in the stimulation of oxidative stress by chronic tobacco exposure because cigarette smoke exposure resulted in the activation of Nrf2 mRNA expression that counteract the immense oxidative stress that accompanies this trigger

Witko-Sarsat V, Friedlander M, Nguyen-Khoa T, Capeillre-Blandin C, Nguyen AT, Canteloup S, Dayer JM, Jungers P, Dreke T, Descamps-Latscha B (1998) Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure