glutathione s transferase sequence pgex transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases The role of glutathione-S-transferase in
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10.1089/ars.2017.7230 3
[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Gao M, Monian P, Quadri N, Ramasamy R, Jiang X
799 Additionally, due to variations among patients in genetics, environment, diet, and lifestyle, the heterogeneity of cancer microenvironments makes it challenging to identify universal metabolic targets
359,360,362 These studies highlight that targeting ferroptosis in TAMs is promising to eliminate pro-tumorigenic M2 macrophages or reprogram TAMs towards a tumoricidal M1 type, thereby inhibiting tumor progression
