b12 injection in foot Injections for Neuropathy Relief: Success Story Vitamin B12 - Ideal Foot
Description
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloidogenic processing in mice

not from a controlled trial

The University of Michigan also warns that a B12 shot is not recommended for people with Lebers disease (7)

[12] It is used in pediatric patients with intrinsic cobalamin metabolic diseases, vitamin B 12 -deficient patients with tobacco amblyopia due to cyanide poisoning, and patients with pernicious anemia who have optic neuropathy