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In addition, considering the serotonin system ( i.e

Core-shell structured microneedles with programmed drug release functions for prolonged hyperuricemia management

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Mechanistically, hyperactivation of Drp1 suppresses hexokinase 1 (HK1), a glycolytic enzyme localized to the mitochondria, inducing metabolic reprogramming that promotes NLRP3-driven inflammation and oligodendrocyte pyroptosis (Pradeepkiran and Reddy, 2020