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One theory suggests that oxidative stress may underlie different diseases, including mental health and brain disorders, heart disease, diabetes, and more
As both glutamine and glucose are important for the TCA cycle, it has been speculated that enhanced SLC7A11 export of glutamate in cancer cells makes them more dependent on glucose to replenish the TCA cycle (50, 51)
In addition, the anti-tumor efficacy was also confirmed by H&E staining, as shown in Supplementary Fig
3-
