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Stage II (mild) 6-15

It is worth noting that alterbrassicene A ( 21 ) displayed an inhibitory effect against IKK (IC 50 = 2.48 M), and it could bind to KD N and C lobes of IKK through hydrogen bond interactions with Leu21 and Arg31 [140]
[DOI] [PubMed] [Google Scholar] 60.Sridhar BV, Brock JL, Silver JS, Leight JL, Randolph MA, Anseth KS

Baltazar F, Afonso J, Costa M, Granja S