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For additional descriptions of our previously finalized policies for the HAC Reduction Program, we also refer readers to the following final rules: The FY 2014 IPPS/LTCH PPS final rule (78 FR 50707 through 50729)

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In neurodegenerative disorders such as Alzheimers and Parkinsons diseases, alpha-lipoic acid has gained attention for its ability to reduce the accumulation of misfolded proteins within mitochondria (via mtUPR), as well as mitigate the excessive production of ROS, protecting neurons against mitochondrial dysfunction [75, 76]