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In in vivo tests, the PMP-PI group showed better therapeutic outcomes than the PMP-P group, as indicated by healthier lung tissue appearance, reduced hemorrhage, lower lung weight, and less edema ( Figure 3M )

When cognate antigen is found, T cells begin to exit quiescence toward proliferation, survival and differentiation, three outcomes promoted by: cell cycle entry, cell growth, IL-2 signaling and an increase in flux through metabolic pathways that sustain anabolism (47)

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