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Prevention is key in avoiding or controlling itching and irritation, so patients are advised to make several lifestyle changes, such as avoiding harsh cleansers and opting for lukewarm showers, to prevent exacerbation of this uncomfortable disease [57,110,126]

[71] in endurance athletes and sprinters, supplemented with 2 g of oral L-carnitine/day for 4 months, no changes in L-carnitine contents in skeletal muscle at rest were noticed

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32 Oxidative stress, generated by tobacco smoke and augmented by ROS generated from both inflammatory cells and mitochondrial activity by cells resident in the respiratory tract, regulate mucous cell metaplasia and mucin gene expression such as MUC5AC and MUC5B