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Among the most important are the degeneration of dopaminergic neurons and the loss of the substantia nigra, combined with the intracellular aggregation of -synuclein, which forms Lewy bodies and neurites [7]
PMID: 34799272 3 Glutaric Aciduria Type 1 and Acute Renal Failure: Case Report and Suggested Pathomechanisms
According to the Randle hypothesis the fatty acid-induced insulin resistance will result in elevated intracellular levels of both glucose and glucose-6-phosphate (Figure 7)
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