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It is possible that this may be similarly implicated in lung inflammation and injury given the now recognized importance of necrosis in regulation cell death pathways and the influence this has in pathological disease

Annals of Clinical & Laboratory Science 36(3):347, 2006

Discontinuation may be warranted if allergic reactions occur, if side effects persist despite slower dosing, or if baseline conditions (acute kidney injury, active infection) change

Some patients may notice symptoms returning before their next scheduled injection, particularly if they have higher metabolic demands or ongoing neurological involvement