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Their capacity for cargo transfer, elevated stability, extended half-life in circulation, and advantageous safety profile render them appealing options for the identification and management of multiple ailments, including respiratory disorders

Under pathological conditions, however, an imbalance between free radical formation and its elimination by antioxidants results in a state of oxidative stress

Although the use of targeted metabolite tracing, such as deuterium tracing of NADPH [7], is successful and remains the gold standard in the field, this approach requires mass-spectrometry, which may not be accessible to many laboratories