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Cancers 2011;3:12851310

Insights on the involvement of (-)-epigallocatechin gallate in er stress-mediated apoptosis in age-related macular degeneration

This hypothesis has led to the development of drugs, including -secretase inhibitors, -secretase inhibitors and modulators, anti-amyloid antibodies, A vaccine, and A aggregation inhibitors, aimed at delaying the diseases advancement

This enzyme is known as 8-oxoguanine DNA glycosylase 1 (OGG1), and it assists in the release of adducts into the extracellular space through the excision of DNA base adducts (154, 155)