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Because its level in the blood is almost entirely dependent on the kidneys, it is a sensitive marker of renal function and is used to estimate GFR (Levey 1999)
ROS plays a role in cancer progression, promoting various cellular processes despite causing mutagenesis
& Cooper, B
studied the relative contribution of visceral (VAT) and subcutaneous (SAT) adipose tissue to cardiometabolic disease by dissecting abdominal adipose tissue in VAT and SAT with ultrasonography and assessed the specific association of these types of adipose tissue with metabolic syndrome and its constitutive features including hyperuricemia and raised liver enzymes compared to adipose tissue assessed by waist circumference [42]
