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Description
The whole process occurs via the classical pathway for complement activation, which is comprised of a variety of complement component bodies such as C2, C4, C3a, C4a, C5a, etc
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PAs beneficial effects might be attributed to iron chelation, decreased CYP2E1 mRNA expression, increased SIRT -1 expression at both mRNA and protein levels, and decreasing oxidative stress
Oxidative stress is critical in the pathophysiology of low back pain, as it has been shown to accelerate low back pain progression
