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This excluded studies with inconsistent methodologies and standards and identified significant impairments in visuo-spatial, short-term, and especially immediate memory, with impacts on working memory being consistent with a massive executive deficit in patients [16]

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ChREBP-deficient mice have decreased lipogenesis as well as reduced expression of ACC, ACLY, and FASN, but unchanged levels of SREBP-1c, suggesting that ChREBP and SREBP proteins are both required for the regulation of lipid synthesis genes (137)

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