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Oxidative stress and depletion of cellular GSH are considered key factors in the onset and progression of various chronic and age-related disorders

These aldehydes modify critical proteins via adduct formation, alter intracellular signaling, and promote the activation of NF-B and other pro-inflammatory pathways [34,35], which exacerbate local inflammation and contribute to the systemic oxidative burden observed in psoriatic patients [36]

Supports nitric oxide production and anti-catabolism

Abstract Ferroptosis is a new type of cell death that was discovered in recent years and is usually accompanied by a large amount of iron accumulation and lipid peroxidation during the cell death process