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intracellular half-life is prolonged because of lysosomal release and cytosolic resequestration, creating a depot effect that supports monthly maintenance dosing for chronic deficiencies

Eligibility & Dose Requirements Proof of your current prescription and dosage is required during your consultation. Your provider will verify your eligibility and determine the appropriate dose based on your treatment history. To qualify for 4.4mg/week, you must have been prescribed at least 2.2mg/week within the past 45 days. To qualify for 7mg/week, you must have been prescribed at least 4.4mg/week within the past 45 days. To qualify for 10mg/week, you must have been prescribed at least 7mg/week within the past 45 days. Patients requesting 13mg/week must have documentation of prior treatment at an appropriate dose, as determined by the prescribing provider

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Unnecessary vitamin B12 shots costing Ontario millions, study finds Most seniors getting B12 shots in province don't need them, researchers say Almost two-thirds of Ontario seniors who received vitamin B12 shots had no evidence of a B12 deficiency, according to a study published in the medical journal JAMA Internal Medicine