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DOSE ADJUSTMENTS AND TSH MONITORING Careful dose titration is necessary to avoid the consequences of over- or undertreatment

doi: 10.1007/s11033-020-05626-w

Harmsen E, de Jong JW, Serruys PW: Hypoxanthine production by ischemic heart demonstrated by high pressure liquid chromatography of blood purine nucleosides and oxypurines
Studies on animal models were also included