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Description
These beads were then collected and washed five times with lysis buffer, after which protein sample buffer was added

27 Elevated levels of several of these metals have also been reported in the substantia nigra of PD subjects

Reference Cummins, Cole and Edwards1999

An invasive approach includes delivery of medication directly to the brain through injection/surgical implants or disruption of the tight endothelial junction of the BBB to facilitate drug penetration
