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This is especially important for pediatric patients

While this data comes from combination therapy, it reflects the profound metabolic effects of amylin receptor activation

For example, PHH spheroids were gradually adapted to ACF media over 3 weeks to achieve comparable performance to that of spheroids cultured under FBS-containing conditions, starting with a medium composed of 50% serum-free formulation (Mickols et al., 2025)

Geographically, North America generated the highest revenue in 2022 accounting for over 45% of the market, but the Asia-Pacific region is expected to experience the most significant growth through 2030