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On top of that, the injectable form carries the same practical drawbacks as other injectable peptides: needles, sterile reconstitution, refrigeration, degradation after mixing, and the ongoing friction of maintaining a regular injection routine for benefits that build gradually over months

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Studies have shown that crocin can improve the histopathological changes caused by doxorubicin (Razmaraii et al., 2016), and attenuated the cardiotoxicity induced by diazinon (Razavi et al., 2013)
Reference Bouov, Hjek, Drata and Sklov2012
