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Reactions were performed with 0.5 M catechol substrate COMT-S01, 1 M radiolabelled S-adenosyl-L-[methyl- 3 H] methionine (SAM) co-substrate, and recombinant human COMT enzyme

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After the initial phase, your treatment will depend on whether your vitamin B12 shortage is caused by your food or whether it is resulting in any neurological issues, such as issues with thinking, memory, and behaviour, Dr Aravinda commented