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Nature Metabolism 2026 , 67 Aya Bassatne, Ivania Rizo

Use of CDT-4 is limited to use in programs administered by the Centers for Medicare & Medicaid Services (CMS)

The actual treatment is typically quick, taking around 30 minutes

Smaller nanoparticles (typically less than 100 nm) are more likely to pass through the BBB because they are more easily taken up by brain endothelial cells (Nowak et al., 2020)
