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Furthermore, NADPH itself functions as a potent GPx inhibitor, potentially compromising assay accuracy [15]

In any case, the most commonly shared hallmark of different forms of cholestasis is an interruption of the enterohepatic circulation of bile acids and consequent retention of toxic bile salts in the bloodstream and at the intracellular level, leading to fibrosis and cirrhosis [173]

Substances that raise GSH levels are being used with increasing frequency in the field of toxicology with considerable success

Oncotarget 6 , 2439324403