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Cell 6 , 517526 (2000)
doi: 10.2337/dc14-2093 253
Acknowledgments The authors extend their appreciation to the Deanship of Research and Graduate Studies at King Khalid University for funding this work through the Large Research Project under grant number R.G.P2/330/46
At concentrations of 1 pM1 nM, DSIP stimulated calcium-dependent release of immunoreactive Met-enkephalin from rat lower brainstem slices in vitro suggesting any antinociceptive effects observed in animal models may be mediated through endogenous opioid peptide release rather than direct receptor binding [7]
