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Transferrin (indirectly measured via TIBC) is a negative acute phase protein and will decrease (more slowly than iron) with inflammation

10.3389/FIMMU.2021.791565 36

These findings indicate that H 2 O 2 treatment promotes the expression of DKK3 while inhibiting the expression of GSTM1 in SRA01/04 lens epithelial cells

doi: 10.3390/ijerph20043752