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Specific to bone, the genetic global deletion of pro-inflammatory cytokines such as IL-6 and TNF- can protect mice from HFD-induced trabecular bone loss (519, 566)

2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one) is another flavonol commonly found in fruits and vegetables, particularly in strawberries (160 g/g) and apples (27 g/g), mostly in glycoside form
Br J Cancer 67:680685 Tisdale MJ (2008) Catabolic mediators of cancer cachexia

(PubMed) Polireddy K, Dong R, Reed G, et al
