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It has been demonstrated that short term administration of an oral carnitine compound, glycine propionyl-L-carnitine (GPLC), produces significantly elevated levels of nitric oxide metabolites at rest in both sedentary and trained persons [6, 7]

Lin et al

This inefficient process produces excessive lactic acid, alters cellular pH, and causes microscopic muscle damage that can take days or weeks to repair

These patients experience accumulation of plasma acylcarnitines, in part due to a decreased renal clearance of esterified carnitine moieties [54]
