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Moreover, partial meniscectomy, though considered less invasive, still results in long-term joint degeneration, especially when combined with factors such as limb malalignment or ACL deficiency (Zhang H

However, a delay in neuronal differentiation and gliogenesis was later reported in the spinal cord of Gdf11 -null mice, suggesting that GDF11 promotes the temporal progression of neurogenesis in the developing spinal cord 57