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When the demand is not met, the significance rises

SCFAs are the primary energy source for many epithelial cells, and a wealth of evidence indicates that SCFAs induce a tightening effect on tight junction permeability

Nicotinic acid-induced vasodilation may be related to release of histamine and/or prostacyclin

Larazotide acetate for persistent symptoms of celiac disease despite a gluten-free diet: a randomized controlled trial
