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If the solution looks cloudy, has changed color, or contains floating debris, the vial is compromised and must be discarded immediately, regardless of the expiration date

[Google Scholar] Hasnain M

When intracellular GSH/GSSG ratio is decreased, critical thiols located on the active site of key enzymes can be oxidized forming intra- or inter-protein disulfide, affecting signaling capacity
[DOI] [PubMed] [Google Scholar] 119.Bocca C., Novo E., Miglietta A., Parola M
