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[DOI] [PMC free article] [PubMed] [Google Scholar] Granlund I, Storm P, Schubert M, Garca-Cerdn JG, Funk C, Schrder WP

We previously produced the App NL-G-F/NL-G-F -KI ( App NL-G-F ) mouse strain using genomic DNA of introns 15 to 17 of mouse APP, which humanized the A sequence, and introduced KM670/671NL (Swedish), I716F (Iberian), and E693G (Arctic) mutations 41

Although it catalyzes the metabolism of methionine, homocysteine (Hcy) is an amino acid typically not involved in protein synthesis

10.2337/diabetes.54.4.1123 42 GalvanD
