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Augmentation strategies for treatment resistant major depression: a systematic review and network meta-analysis

The combination of the lysosome disruptor siramesine and the tyrosine kinase inhibitor lapatinib increased the expression of TF and reduced the expression of FPN1 in breast cancer cells, thereby promoting iron overload in the lysosome and ultimately inducing ferroptosis ( Ferroptosis could be induced by directly supplementing the cell's active iron pool to establish an iron overload state

Rare Side Effects In addition to common side effects, there are rare instances where individuals may experience more severe reactions: Asthma Symptoms : Those with asthma may experience exacerbated symptoms, such as wheezing or shortness of breath

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